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Quality Assurance2026-08-10

How to Read Peptide COA Reports

How to Read Peptide COA Reports

COA (Certificate of Analysis) is the core quality document for peptide products, containing key indicators such as purity, molecular weight, and sequence confirmation.

Key Indicators Interpretation

  • Purity: Determined by HPLC, typically required ≥99%
  • Molecular Weight: Confirmed by mass spectrometry, deviation from theoretical value should be <0.1%
  • Sequence Confirmation: Verified by amino acid analysis or mass spectrometry
  • Water Content: Determined by Karl Fischer method
  • Bacterial Endotoxin: Ensure compliance with pharmacopeia standards

How to Verify COA Authenticity

A legitimate COA report should include: batch number, production date, test methods, test results, tester's signature, and quality control department seal. Authenticity can be verified by contacting the manufacturer.